Novel Pharmacotherapy for Hypertrophic Cardiomyopathy.

Department of Medicine, Division of Cardiology, University of Pittsburgh School of Medicine, UPMC Hypertrophic Cardiomyopathy Center, UPMC Heart and Vascular Institute, 200 Lothrop Street, Pittsburgh, PA 15213, USA. Electronic address: wongtc@upmc.edu. Division of Cardiology, Lehigh Valley Health Network, 1250 South Cedar Crest Boulevard, Suite 300, Allentown, PA 18103, USA.

Cardiology clinics. 2019;(1):113-117

Abstract

Medical therapy for hypertrophic cardiomyopathy (HCM) has focused on minimizing the impact of symptoms due to left ventricular outflow tract obstruction and diastolic dysfunction. This article briefly discusses currently available therapy and focuses on both clinically available medications with novel applications for HCM as well as novel medications under development with specific indication for HCM. Finally, a brief summary of the current gaps and potential targets for pharmacotherapy is discussed.

Methodological quality

Publication Type : Review

Metadata